BEYOND THE CLASSROOMBeyond the classroom.
Beyond the classroom.
Biology out in the world.
Follow classroom ideas into careers, research, medicine, the environment and the claims you meet in everyday life. Choose a unit, open a topic, then follow an activity to its lesson. Each activity starts from the specification and gives you a question to think through.
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Open a unit, then a topic, to find its activities.
Unit 1Molecules, Diet, Transport and HealthTopic 1 · Topic 272 activities
Topic 1Molecules, Transport and Health36 activities
- Water carries a chemical story1A · The Chemistry of Life
- Why water cannot wash away an oil spill1A · The Chemistry of Life
- The chemistry behind lactose-free milk1A · Carbohydrates 1: Monosaccharides and Disaccharides
- Can a blue test tube prove a drink has no sugar?1A · Carbohydrates 1: Monosaccharides and Disaccharides
- Could starch become packaging?1A · Carbohydrates 2: Polysaccharides
- What are endurance athletes actually storing?1A · Carbohydrates 2: Polysaccharides
- What does an oil label really tell you?1A · Lipids
- From used cooking oil to fuel1A · Lipids
- A small sequence change, a large consequence1A · Proteins
- Can AI predict a protein’s shape?1A · Proteins
- A name is not a structure1A · Thinking Bigger: Trehalose
- Keeping an organ supplied outside the body1B · The Principles of Circulation
- The scientist who runs a temporary circulation1B · The Principles of Circulation
- Why donated blood is separated1B · The Roles of the Blood
- What does an oxygen reading really measure?1B · The Roles of the Blood
- When a one-way system leaks1B · Circulation in the Blood Vessels
- Can scientists manufacture a replacement artery?1B · Circulation in the Blood Vessels
- Seeing flow rather than guessing from a heartbeat1B · The Mammalian Heart
- A replacement valve is a biological trade-off1B · The Mammalian Heart
- More than “clogged pipes”1B · Atherosclerosis
- Plastic in an artery: discovery or proof?1B · Atherosclerosis
- What is hidden behind “double the risk”?1C · Risk, Correlation and Cause
- When “same category” does not mean “same risk”1C · Risk, Correlation and Cause
- Following families across generations1C · Investigating the Causes of CVDs
- Can a menu become a controlled experiment?1C · Investigating the Causes of CVDs
- Why a warning needs more than a slogan1C · Risk Factors for Cardiovascular Disease
- A heatwave is also a cardiovascular event1C · Risk Factors for Cardiovascular Disease
- Can a single number describe health?1C · Diet and Cardiovascular Health
- High cholesterol can run in a family1C · Diet and Cardiovascular Health
- The test is the outcome1C · Dietary Antioxidants and Cardiovascular Disease
- Does the vitamin C on the label survive?1C · Dietary Antioxidants and Cardiovascular Disease
- Turning many papers into a useful conclusion1C · Using the Evidence
- Half a million volunteers can still be biased1C · Using the Evidence
- Why “best medicine” needs a context1C · The Benefits and Risks of Treatment
- Testing a side effect without dismissing it1C · The Benefits and Risks of Treatment
- Measuring function rather than guessing1C · Thinking Bigger: Heart Failure
Topic 2Membranes, Proteins, DNA and Gene Expression36 activities
- A channel with a measurable job2A · Cell Membranes
- Getting a message through a membrane2A · Cell Membranes
- Why “stronger alcohol” is not the whole answer2A · Cell Membranes
- A membrane as part of a treatment system2A · Cell Transport and Diffusion
- Why some medicines work as a patch2A · Cell Transport and Diffusion
- Water has specialised routes2A · Osmosis: A Special Case of Diffusion
- Making drinking water by reversing the usual flow2A · Osmosis: A Special Case of Diffusion
- Why rehydration research uses transport biology2A · Active Transport
- A medicine that blocks a glucose carrier2A · Active Transport
- An artificial lung still needs gradients2A · The Need for Gas Exchange Surfaces
- A lung interface on a microchip2A · The Need for Gas Exchange Surfaces
- Why a larger air space can exchange less gas2A · The Mammalian Gas Exchange System
- Why wildfire smoke can reach deep into a lung2A · The Mammalian Gas Exchange System
- Joining exposure data to biology2A · Thinking Bigger: Asthma and Air Pollution
- Catalysis in the washing machine2B · Enzymes
- Can an enzyme recycle a plastic bottle?2B · Enzymes
- Selecting enzymes for a new task2B · How Enzymes Work
- The enzyme inside a glucose sensor2B · How Enzymes Work
- Shakespeare written in DNA2B · The Structure of DNA and RNA
- Jurassic Park needs more than an amber mosquito2B · The Structure of DNA and RNA
- An experiment that separates explanations2B · How DNA Works
- Molecular photocopying has a template problem2B · How DNA Works
- Cracking the code2B · The Genetic Code
- Could a cell use fewer genetic code words?2B · The Genetic Code
- Seeing the protein-making machinery2B · DNA and Protein Synthesis
- A medicine written as a temporary message2B · DNA and Protein Synthesis
- A tumour’s sequence is evidence2C · Gene Mutation
- A mutation is not automatically a tumour2C · Gene Mutation
- Explaining a probability clearly2C · Patterns of Inheritance
- Gattaca: a genotype is not a complete biography2C · Patterns of Inheritance
- Information should survive a colour change2C · Sex Linkage
- The royal family tree meets DNA evidence2C · Sex Linkage
- One protein, several specialist teams2C · Cystic Fibrosis: A Genetic Disease
- Why one CF medicine does not fit every mutation2C · Cystic Fibrosis: A Genetic Disease
- What embryo testing can tell you2C · Genetic Screening
- A negative DNA test is not an all-clear for life2C · Genetic Screening
Unit 2Cells, Development, Biodiversity and ConservationTopic 3 · Topic 471 activities
Topic 3Cell Structure, Reproduction and Development34 activities
- Beyond the conventional light microscope3A · Observing Cells
- Freezing molecules to see their shape3A · Observing Cells
- Interpreting a real cell section3A · Eukaryotic Cells 1: Common Cellular Structures
- The stain that makes a diagnosis possible3A · Eukaryotic Cells 1: Common Cellular Structures
- Cellular delivery addresses3A · Eukaryotic Cells 2: Protein Transport
- Vesicles need the right destination3A · Eukaryotic Cells 2: Protein Transport
- Useful extra DNA3A · Prokaryotic Cells
- The mobile resistance gene3A · Prokaryotic Cells
- Why an organoid is a model3A · The Organisation of Cells
- How a tissue sample becomes a clinical answer3A · The Organisation of Cells
- Discovering the controls3B · The Cell Cycle
- When cell-cycle control is lost3B · The Cell Cycle
- From cells to a research question3B · Mitosis
- Two ways of counting growth3B · Mitosis
- Breeding begins with chromosome behaviour3B · Sexual Reproduction and Meiosis
- When chromosomes do not separate3B · Sexual Reproduction and Meiosis
- The work of an embryologist3B · Gametes: Structure and Function
- What a semen analysis can and cannot show3B · Gametes: Structure and Function
- Fertilisation outside the body3B · Fertilisation in Mammals and Plants
- Two fusions inside a flower3B · Fertilisation in Mammals and Plants
- A clinical technique is not a guarantee3B · Thinking Bigger: Male Infertility
- Why “shuffling” needs a mechanism3B · Exam Practice
- Reprogramming a specialised cell3C · Cell Differentiation
- The axolotl challenges a simple cell story3C · Cell Differentiation
- Quantitative genetics3C · Interactions Between Genes and the Environment
- What identical twins reveal, and do not reveal3C · Interactions Between Genes and the Environment
- Mapping gene regulation3C · Controlling Gene Expression
- A medicine that changes RNA processing3C · Controlling Gene Expression
- Induced pluripotency3C · Stem Cells
- A stem-cell claim needs a safety question3C · Stem Cells
- An established use: blood-cell production3C · Using Stem Cells
- An experimental retinal-cell patch3C · Using Stem Cells
- Microbes as a research field3C · Thinking Bigger: Microbiota
- Looking beyond a gene count3C · Exam Practice
Topic 4Plant Structure and Function, Biodiversity and Conservation37 activities
- Why cellulose is a structural fibre4A · The Cell Wall
- Plant walls record a tree’s history4A · The Cell Wall
- Growing plants where sunlight is engineered4A · Plant Organelles
- A vertical farm still needs plant biology4A · Plant Organelles
- Why a plan is a scientific drawing, not decoration4A · Plant Stems
- Where flax fibres sit in a stem4A · Plant Stems
- Reading a leaf as a nutrient clue, not a diagnosis app4A · The Importance of Water and Minerals in Plants
- The hidden cost of too many nutrients4A · The Importance of Water and Minerals in Plants
- Whole plant cells as a composite4A · Using Plant Starch and Fibres
- Flax composites: strength is only one number4A · Using Plant Starch and Fibres
- Plant medicines still need evidence4A · Plant-based Medicines
- From a plant extract to an antimalarial4A · Plant-based Medicines
- Reading the 1785 book as a source4A · Developing New Drugs
- What a registered trial record tells you4A · Developing New Drugs
- Useful plants are still being documented4A · Exam Practice
- Why the code still matters4B · Principles of Classification
- A museum specimen becomes a DNA reference4B · Principles of Classification
- A species as a gene pool4B · What Is a Species?
- Look-alike bees, different species?4B · What Is a Species?
- Reading the 1990 proposal4B · Domains, Kingdoms or Both?
- A domain diagram can change with evidence4B · Domains, Kingdoms or Both?
- The first extinct-animal sequences4B · Thinking Bigger: The Quagga
- Taxonomy as a public, editable argument4B · Exam Practice
- An intergovernmental snapshot, not a mark scheme4C · Biodiversity and Endemism
- Why island endemics are vulnerable4C · Biodiversity and Endemism
- A global catalogue is not D4C · Measuring Biodiversity
- DNA traces are not a head count4C · Measuring Biodiversity
- Adaptation is a population process4C · Adaptation to a Niche
- A moth’s colour and its niche4C · Adaptation to a Niche
- Why a “no change” equation is still biology4C · Gene Pool and Genetic Diversity
- Genetic rescue has limits4C · Gene Pool and Genetic Diversity
- Speciation is evolution at the gene-pool boundary4C · Reproductive Isolation and Speciation
- A new plant lineage after chromosome doubling4C · Reproductive Isolation and Speciation
- A backup of backups4C · Conservation: Why and How?
- From breeding programme to wild survival4C · Conservation: Why and How?
- Reading a status, not a slogan4C · Thinking Bigger: Orang-utans
- Conservation as a coordinated claim4C · Exam Practice
Unit 4Energy, Environment, Microbiology and ImmunityTopic 5 · Topic 687 activities
Topic 5Energy Flow, Ecosystems and the Environment45 activities
- The enzyme that harvests a gradient5A · The Importance of ATP
- Can sunlight be turned into a stored fuel?5A · The Importance of ATP
- Chlorophyll seen from orbit5A · Chloroplasts and Chlorophyll
- A pigment fingerprint from space5A · Chloroplasts and Chlorophyll
- How the cycle was mapped5A · The Biochemistry of Photosynthesis
- Watching the water-splitting machinery work5A · The Biochemistry of Photosynthesis
- The prize citation, in context5A · Thinking Bigger
- Why a green ocean patch is not a chromatogram5A · Exam Practice
- Ecosystems as energy-transfer systems5B · What Is Ecology?
- The camera trap sees a population, not an ecosystem5B · What Is Ecology?
- Recovery is not a blank page5B · How Ecosystems Evolve
- A buried forest waiting for disturbance5B · How Ecosystems Evolve
- Why field ecologists still carry meters5B · The Effect of Abiotic Factors on Populations
- A reef turns white under stress5B · The Effect of Abiotic Factors on Populations
- Competition is one interaction among several5B · The Effect of Biotic Factors on Populations
- Disturbance changes the invasion story5B · The Effect of Biotic Factors on Populations
- Why the world is not one winner per habitat5B · Ecosystem Interactions and the Importance of the Niche
- Warblers share a tree without sharing a niche5B · Ecosystem Interactions and the Importance of the Niche
- Why textbooks still talk about frames5B · Investigating Abundance and Distribution of Organisms
- A quadrat size can change the answer5B · Investigating Abundance and Distribution of Organisms
- p = 0.05 is a convention5B · Statistics and Ecology
- A wildlife app is not a random sample5B · Statistics and Ecology
- Frames, tapes and honesty about bias5B · Exam Practice
- An energy pyramid needs a measurement5C · Transfers Between Trophic Levels
- Plankton fuel an ocean food web5C · Transfers Between Trophic Levels
- A green map is not GPP5C · Net Primary Productivity
- Measuring a planet’s net production5C · Net Primary Productivity
- Fast cycle, slow cycle5C · The Carbon Cycle in Nature
- Carbon sinks into the deep sea5C · The Carbon Cycle in Nature
- NASA’s blanket, with numbers left off the syllabus5C · Greenhouse Gases and Climate Change
- The greenhouse blanket has different threads5C · Greenhouse Gases and Climate Change
- The professional tree-ring bank5C · Looking at the Evidence
- Air trapped in ancient ice5C · Looking at the Evidence
- Process is part of the evidence5C · The Global Warming Debate: Correlation or Causation?
- Who checks an assessment report?5C · The Global Warming Debate: Correlation or Causation?
- A laboratory we cannot build in the field5C · Models of Climate Change and Their Limitations
- A climate model is tested against yesterday5C · Models of Climate Change and Their Limitations
- The calendar of living things5C · The Biological Impact of Climate Change
- A spring diary becomes research data5C · The Biological Impact of Climate Change
- Speciation is isolation plus time5C · Climate Change and Evolution
- Finches show selection within a lifetime5C · Climate Change and Evolution
- Mitigation that uses land has side-effects5C · What Can Be Done?
- The offset advert leaves out the land5C · What Can Be Done?
- The world’s climate lumber room5C · Thinking Bigger
- One report, many chapters5C · Exam Practice
Topic 6Microbiology, Immunity and Forensics42 activities
- TMV was a tool before it was a syllabus name6A · Bacteria and Viruses
- The Ebola image is a structure, not a monster6A · Bacteria and Viruses
- Phage as a laboratory switch, not a medicine6A · How Viruses Reproduce
- The hidden HIV reservoir6A · How Viruses Reproduce
- The school flask is not an industrial fermenter6A · The Growth of Bacterial Colonies
- Lag phase is busy, even when the curve is flat6A · The Growth of Bacterial Colonies
- The same principles as a professional bench6A · Microbial Techniques
- A cleanroom is aseptic technique at scale6A · Microbial Techniques
- Why a brewery still plates as well as reading a meter6A · Measuring the Growth of Bacterial Cultures
- Cloudy is not the same as alive6A · Measuring the Growth of Bacterial Cultures
- Flora as ecology on a person6A · Invading the Body
- Your skin is occupied territory6A · Invading the Body
- Through the air, not from surfaces6A · Case Studies of Disease: Tuberculosis
- Inside an infected lung cell6A · Case Studies of Disease: Tuberculosis
- HIV is the virus; AIDS is a stage6A · Case Studies of Disease: HIV/AIDS
- Antiretroviral drugs interrupt a life cycle6A · Case Studies of Disease: HIV/AIDS
- A teaching virus that earned its place6A · Thinking Bigger
- Principles, not a photocopied SOP6A · Exam Practice
- NIAID’s innate layer is this page in other words6B · Non-specific Responses to Infection
- A warning message to neighbouring cells6B · Non-specific Responses to Infection
- NIAID’s adaptive layer is clonal and specific6B · The Specific Response to Infection
- An antibody becomes a cancer medicine6B · The Specific Response to Infection
- CDC: vaccines train; they are not antibody drips6B · Developing Immunity
- What an mRNA vaccine actually supplies6B · Developing Immunity
- NHS antibiotics are not a virus medicine6B · Antibiotics: Treating Bacterial Disease
- Killing bacteria is not the only useful outcome6B · Antibiotics: Treating Bacterial Disease
- WHO: resistance is selected, not invented in a ward cupboard6B · Antibiotic Resistance
- The hospital pharmacist as an evolution manager6B · Antibiotic Resistance
- How vaccines work, in CDC’s sentence6B · Thinking Bigger
- Cause, then rule6B · Exam Practice
- Compost is managed decomposition6C · Microorganisms and Decomposition
- Compost versus landfill: the oxygen test6C · Microorganisms and Decomposition
- Forensic work is measurement with a method6C · Forensic Science and the Time of Death
- A time-of-death estimate is a range6C · Forensic Science and the Time of Death
- A life stage is evidence only with a method6C · The Process of Decay
- Maggots can heat their own clock6C · The Process of Decay
- PCR is amplification, not a result by itself6C · Polymerase Chain Reaction (PCR)
- PCR finds a species without seeing it6C · Polymerase Chain Reaction (PCR)
- Length, not a name printed on the band6C · DNA Profiling
- A DNA band is not a verdict6C · DNA Profiling
- Difficult DNA is a methods problem6C · Thinking Bigger
- Methods first6C · Exam Practice
Unit 5Respiration, Internal Environment, Coordination and Gene TechnologyTopic 7 · Topic 878 activities
Topic 7Respiration, Muscles and the Internal Environment39 activities
- The large yield needed a mechanism, not a bigger explosion7A · Respiration in Cells
- When mitochondria cannot meet demand7A · Respiration in Cells
- A lactate number is a blood test7A · Glycolysis and Anaerobic Respiration
- Cancer cells rewrite the glycolysis story7A · Glycolysis and Anaerobic Respiration
- The carbon dioxide in your breath was chemistry first7A · The Krebs Cycle
- Carbon can leave before the chain begins7A · The Krebs Cycle
- The gradient was the disputed idea7A · The Electron Transport Chain
- Brown fat spends a gradient on heat7A · The Electron Transport Chain
- Yeast is a cell with a metabolism, not an RQ chart7A · Respiratory Substrates and Respiratory Quotient
- A fuel leaves a signature in two gases7A · Respiratory Substrates and Respiratory Quotient
- Same gases, different process7A · Exam Practice
- Sprain and strain are not the specification pair7B · Tissues of the Skeletal System
- A prosthetic joint still needs opposing pulls7B · Tissues of the Skeletal System
- A pulled muscle is not a labelled sarcomere7B · What Is Muscle?
- A muscle fibre has machinery within machinery7B · What Is Muscle?
- Endurance and injury are different conversations7B · Different Types of Muscle Fibre
- Fibre types are a continuum, not a sports horoscope7B · Different Types of Muscle Fibre
- Soreness is not a cross-bridge diagram7B · How Muscles Contract
- Why a stopped ATP supply stiffens muscle7B · How Muscles Contract
- An ECG records rhythm, it does not finish the medicine7B · Cardiac Muscle and Control of the Heartbeat
- A pacemaker assists a conduction system7B · Cardiac Muscle and Control of the Heartbeat
- Heat illness is failed balance, not a new definition7B · Principles of Homeostasis
- Feedback is measured over time7B · Principles of Homeostasis
- Activity changes the rate; the node still starts the beat7B · Controlling the Heart and Breathing Rates
- Stress hormones are measurable chemistry7B · Controlling the Heart and Breathing Rates
- Spirometry on the NHS is not this trace7B · The Response of the Breathing System to Exercise
- The exercise mask measures more than a breath count7B · The Response of the Breathing System to Exercise
- The clinical category is broader than one wave7B · Thinking Bigger
- The recording aids a clinician7B · Exam Practice
- Cells keep most genes quiet7C · Homeostasis and Hormones
- A steroid signal reaches the transcription machinery7C · Homeostasis and Hormones
- Filter and reabsorb, then the specification adds the mechanism7C · Osmoregulation in Mammals: The Kidney
- A dialyser is selective in a different way7C · Osmoregulation in Mammals: The Kidney
- A large urine volume can mean the hormone or the response7C · Control of the Kidney and Homeostasis
- Same urine result, two different faults7C · Control of the Kidney and Homeostasis
- Heat exhaustion is not an extra effector7C · Thermoregulation and Exercise
- Heat stress is a failure of balance, not a thermometer fact7C · Thermoregulation and Exercise
- Haemodialysis is not a second nephron7C · Thinking Bigger
- The public filter is the start of the answer7C · Exam Practice
Topic 8Coordination, Response and Gene Technology39 activities
- Light becomes a signal only after a receptor cell8A · The Structure of Neurones
- Myelin damage changes a network, not just one cable8A · The Structure of Neurones
- A receptor starts the pathway the cord then finishes8A · How the Nervous System Works
- After spinal injury, signal direction matters8A · How the Nervous System Works
- A receptor potential is not yet this spike8A · The Neurones in Action
- A local anaesthetic tests the sodium step8A · The Neurones in Action
- The NHS account of Parkinson’s is the cell loss8A · The Effect of Drugs on the Nervous System
- One receptor, very different chemicals8A · The Effect of Drugs on the Nervous System
- Photoreceptors start the electrical story8A · Sensory Systems and the Detection of Light
- Dark adaptation is more than pupil size8A · Sensory Systems and the Detection of Light
- The eye page names detection, not the iris muscles8A · Synapses and Habituation
- A sea slug taught neuroscientists about habituation8A · Synapses and Habituation
- Dopamine loss is not an axon sodium story8A · Exam Practice
- MRI is one way the living brain is pictured8B · The Central Nervous System
- The hypothalamus links two kinds of control8B · The Central Nervous System
- A scan can show the centre the nerves plug into8B · The Peripheral Nervous System
- A peripheral nerve test asks where the fault lies8B · The Peripheral Nervous System
- Activation during a task is not a thought transcript8B · Investigating the Human Brain
- PET traces molecules, not thoughts8B · Investigating the Human Brain
- Read the NHS sentence before you simplify depression8B · The Chemical Balance of the Brain
- A depression headline is not a serotonin assay8B · The Chemical Balance of the Brain
- A hormone can be the signal a transcription factor waits for8B · Chemical Control Systems in Plants
- Plants read the colour of their neighbours8B · Chemical Control Systems in Plants
- Flowering is a transcription decision8B · Phytochrome and Flowering
- A night-time flash can change a flowering signal8B · Phytochrome and Flowering
- The page is human genetics. The logic still fits a seedling.8B · Phytochrome and Transcription
- Malting begins with a gene-expression decision8B · Phytochrome and Transcription
- fMRI observes activation during a task8B · Thinking Bigger
- Use the NIBIB sentence when a question exaggerates8B · Exam Practice
- The same idea made insulin8C · Producing Recombinant DNA
- CRISPR is a different question from cut-and-join cloning8C · Producing Recombinant DNA
- Insulin was the proof the method could make a medicine8C · Drugs from Genetically Modified Organisms
- Insulin was a manufacturing milestone8C · Drugs from Genetically Modified Organisms
- Turned on, then compared8C · Microarrays and Bioinformatics
- A tumour profile measures RNA, not destiny8C · Microarrays and Bioinformatics
- Name the advantage, then name the issue8C · Benefits and Risks of GMOs
- A crop trait needs a case-by-case risk question8C · Benefits and Risks of GMOs
- Computers hold the sequences8C · Thinking Bigger
- Method, product, pattern, judgement8C · Exam Practice