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Question 1 of 10: A diagram shows DNA, pre-mRNA containing alternating labelled introns and exons, mature mRNA and a polypeptide. Describe how more than one protein can be synthesised from RNA produced from one gene.

013.195 marks

One gene, more than one protein

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A strip of DNA is transcribed into pre-mRNA made of nine segments lettered P to X; P, R, T, V and X are introns and Q, S, U and W are exons. After splicing, the mature mRNA contains only Q, S, U and W, which is translated into a polypeptide.DNAtranscriptionPQRSTUVWXpre-mRNAsplicingQSUWmature mRNApolypeptideblue = exons, grey = introns
The pre-mRNA has introns P, R, T, V and X (grey) alternating with exons Q, S, U and W (blue); after splicing the mature mRNA is Q S U W.

Describe how more than one protein can be synthesised from the RNA produced from this one gene.

(5)

Total for this question: 5 marks

Lesson: 3C 3: Controlling Gene Expression