4(b) INHERITANCE · RECALL

4.31 Random fertilisation and variation

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014.31Pearson Edexcel focus

Two sources of variation in sexual reproduction?

Reveal answer

Meiosis (new allele combinations) + random fertilisation.

Key words: random

024.31Lesson

What is meant by the term recombination?

Reveal answer

Production of new allele combinations, including through crossing over.

Key words: recombination

034.31Lesson

What is meant by the term population?

Reveal answer

Members of one species living in the same area at the same time.

Key words: population

044.31Lesson

Sources of inherited variation, Crossing over. When it occurs? Effect?

Reveal answer

When it occurs: Meiosis I. Effect: Recombines alleles within homologues.

Key words: Crossing over

054.31Lesson

Sources of inherited variation, Independent assortment. When it occurs? Effect?

Reveal answer

When it occurs: Meiosis I. Effect: Distributes whole homologues randomly.

Key words: Independent assortment

064.31Lesson

Sources of inherited variation, Random fertilisation. When it occurs? Effect?

Reveal answer

When it occurs: Gamete fusion. Effect: Combines any sperm with any egg.

Key words: Random fertilisation

074.31Lesson

Sources of inherited variation, Mutation. When it occurs? Effect?

Reveal answer

When it occurs: Before/during DNA copying. Effect: Creates new allele sequences.

Key words: Mutation

084.31Lesson

True or false, and why? “Random fertilisation creates new alleles.”

Reveal answer

False. It creates new combinations; mutation creates new allele sequences.

094.31Lesson

True or false, and why? “Siblings have exactly half the same DNA in every region.”

Reveal answer

False. They share ancestry but receive different recombined allele combinations.

104.31Lesson

True or false, and why? “Variation is always useful.”

Reveal answer

False. Its effect depends on the environment and trait.

114.31Pearson Edexcel focus

Why does random fertilisation increase variation?

Reveal answer

Any one of millions of genetically different sperm can fuse with any egg → a huge number of combinations.

Key words: sperm

124.31Pearson Edexcel focus

Do brothers and sisters from the same parents inherit the same alleles?

Reveal answer

No (unless identical twins): each child gets a different mix.

Key words: No

134.31Pearson Edexcel focus

Why are identical twins genetically identical?

Reveal answer

Both develop from one zygote that split.

Key words: one zygote

144.31Pearson Edexcel focus

Suggest why variation helps a species survive a new disease.

Reveal answer

Some individuals may have alleles that give resistance → they survive and reproduce.

Key words: resistance

154.31Pearson Edexcel focus

Which type of reproduction produces genetic variation in the offspring?

Reveal answer

Sexual reproduction.

Key words: sexual

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