3(j) CO-ORDINATION AND RESPONSE · RECALL

3.39 Neurotransmitters at synapses

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013.39Pearson Edexcel focus

How does an impulse cross a synapse?

Reveal answer

Impulse arrives → neurotransmitter released → diffuses across gap → binds receptors → new impulse.

Key words: neurotransmitter · diffuses

023.39Pearson Edexcel focus

Why one-way at synapses?

Reveal answer

Released only on one side, receptors only on the other.

Key words: receptors

033.39Pearson Edexcel focus

What is the gap between neurones called?

Reveal answer

A synapse.

Key words: synapse

043.39Lesson

What is meant by the term synapse?

Reveal answer

Junction through which one neurone communicates with another cell.

Key words: synapse

053.39Lesson

What is meant by the term neurotransmitter?

Reveal answer

Chemical messenger released from a neurone at a synapse.

Key words: neurotransmitter

063.39Lesson

What is meant by the term synaptic cleft?

Reveal answer

Narrow gap between pre- and postsynaptic cells.

Key words: synaptic cleft

073.39Lesson

What is meant by the term reuptake?

Reveal answer

Transport of released neurotransmitter back into the presynaptic cell.

Key words: reuptake

083.39Lesson

Across a synapse: for Presynaptic axon, give the main event and the signal form.

Reveal answer

Main event: Impulse arrives. Signal form: Electrical.

Key words: Presynaptic axon

093.39Lesson

Across a synapse: for Presynaptic ending, give the main event and the signal form.

Reveal answer

Main event: Vesicles release neurotransmitter. Signal form: Electrical → chemical.

Key words: Presynaptic ending

103.39Lesson

Across a synapse: for Synaptic cleft, give the main event and the signal form.

Reveal answer

Main event: Neurotransmitter diffuses. Signal form: Chemical.

Key words: Synaptic cleft

113.39Lesson

Across a synapse: for Postsynaptic membrane, give the main event and the signal form.

Reveal answer

Main event: Receptors bind transmitter and alter ion flow. Signal form: Chemical → electrical.

Key words: Postsynaptic membrane

123.39Lesson

Across a synapse: for After transmission, give the main event and the signal form.

Reveal answer

Main event: Breakdown or reuptake removes transmitter. Signal form: Signal terminates.

Key words: After transmission

133.39Lesson

True or false, and why? “The electrical impulse jumps directly through empty space.”

Reveal answer

False. A neurotransmitter normally diffuses across the cleft.

143.39Lesson

True or false, and why? “Neurotransmitter remains in the cleft permanently.”

Reveal answer

False. It is removed by breakdown, diffusion or reuptake.

153.39Lesson

True or false, and why? “Every synapse always triggers a new impulse.”

Reveal answer

False. Inputs may excite or inhibit, and threshold may not be reached.

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