3(h) TRANSPORT · RECALL

3.12 White blood cells and the immune response

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013.12Pearson Edexcel focus

What do phagocytes do?

Reveal answer

Engulf and digest pathogens (phagocytosis).

Key words: engulf

023.12Pearson Edexcel focus

What do lymphocytes make?

Reveal answer

Antibodies.

Key words: antibodies

033.12Pearson Edexcel focus

What is an antigen?

Reveal answer

A molecule on a pathogen surface that triggers an immune response.

Key words: antigen

043.12Pearson Edexcel focus

How do antibodies work?

Reveal answer

Complementary to antigen → bind → clump pathogens → phagocytes engulf.

Key words: complementary · clump

053.12Pearson Edexcel focus

Why is there a delay in the primary response?

Reveal answer

Lymphocyte must recognise antigen → divide → make antibody.

Key words: divide

063.12Pearson Edexcel focus

Which white cells are non-specific?

Reveal answer

Phagocytes.

Key words: phagocytes

073.12Pearson Edexcel focus

Why does an antibody protect against only one disease?

Reveal answer

Antibodies are specific → fit only one antigen shape.

Key words: specific

083.12Lesson

What is meant by the term phagocytosis?

Reveal answer

Engulfment and digestion of particles or pathogens by a cell.

Key words: phagocytosis

093.12Lesson

What is meant by the term antigen?

Reveal answer

Molecule recognised as foreign and able to trigger a specific immune response.

Key words: antigen

103.12Lesson

What is meant by the term antibody?

Reveal answer

Specific protein that binds a complementary antigen.

Key words: antibody

113.12Lesson

What is meant by the term lymphocyte?

Reveal answer

White blood cell involved in specific immune responses.

Key words: lymphocyte

123.12Lesson

Two white-cell responses: for Specificity, give the phagocyte and the lymphocyte/antibody response.

Reveal answer

Phagocyte: Broad/non-specific. Lymphocyte/antibody response: Antigen-specific.

Key words: Specificity

133.12Lesson

Two white-cell responses: for Action, give the phagocyte and the lymphocyte/antibody response.

Reveal answer

Phagocyte: Engulfs and digests. Lymphocyte/antibody response: Clonal division and antibody release.

Key words: Action

143.12Lesson

Two white-cell responses: for Main tool, give the phagocyte and the lymphocyte/antibody response.

Reveal answer

Phagocyte: Membrane and digestive enzymes. Lymphocyte/antibody response: Complementary receptor/antibody.

Key words: Main tool

153.12Lesson

Two white-cell responses: for Cooperation, give the phagocyte and the lymphocyte/antibody response.

Reveal answer

Phagocyte: Ingests antibody-marked targets. Lymphocyte/antibody response: Marks or neutralises targets.

Key words: Cooperation

163.12Lesson

True or false, and why? “Antibodies kill all pathogens directly.”

Reveal answer

False. They bind specific antigens and neutralise or mark targets; other mechanisms may destroy them.

173.12Lesson

True or false, and why? “Phagocytes make antibodies.”

Reveal answer

False. Antibodies are released by activated lymphocyte-derived plasma cells.

183.12Lesson

True or false, and why? “Every antibody fits every antigen.”

Reveal answer

False. Binding depends on complementary shape and chemistry.

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