4(b) INHERITANCE · RECALL

4.22 Polygenic inheritance

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014.22Lesson

What is meant by the term polygenic?

Reveal answer

Influenced by alleles at several gene loci.

Key words: polygenic

024.22Lesson

What is meant by the term continuous variation?

Reveal answer

Variation across a measurable range with many intermediate values.

Key words: continuous variation

034.22Lesson

What is meant by the term monogenic?

Reveal answer

Mainly controlled by one gene locus in the model.

Key words: monogenic

044.22Lesson

What is meant by the term distribution?

Reveal answer

Pattern of values and their frequencies in a dataset.

Key words: distribution

054.22Lesson

Inheritance and variation patterns: for Number of main loci, give the monogenic model and the polygenic model.

Reveal answer

Monogenic model: One. Polygenic model: Many.

Key words: Number of main loci

064.22Lesson

Inheritance and variation patterns: for Phenotype categories, give the monogenic model and the polygenic model.

Reveal answer

Monogenic model: Often discrete. Polygenic model: Often continuous.

Key words: Phenotype categories

074.22Lesson

Inheritance and variation patterns: for Expected ratios, give the monogenic model and the polygenic model.

Reveal answer

Monogenic model: Simple ratios may apply. Polygenic model: Many combinations blur ratios.

Key words: Expected ratios

084.22Lesson

Inheritance and variation patterns: for Environmental influence, give the monogenic model and the polygenic model.

Reveal answer

Monogenic model: Can occur. Polygenic model: Often substantial.

Key words: Environmental influence

094.22Lesson

Inheritance and variation patterns: for Example, give the monogenic model and the polygenic model.

Reveal answer

Monogenic model: ABO group. Polygenic model: Height.

Key words: Example

104.22Lesson

True or false, and why? “A polygenic trait has one dominant allele.”

Reveal answer

False. Many loci contribute, so simple dominance at one locus cannot describe the whole trait.

114.22Lesson

True or false, and why? “Continuous variation is caused only by environment.”

Reveal answer

False. It can arise from many genes plus environmental effects.

124.22Lesson

True or false, and why? “Genes determine an exact fixed height.”

Reveal answer

False. They influence potential, while environment and development modify outcome.

134.22Pearson Edexcel focus

Give an example of a human characteristic controlled by several genes.

Reveal answer

Skin colour (also height and eye colour).

Key words: skin colour

144.22Pearson Edexcel focus

Why does polygenic inheritance give continuous variation?

Reveal answer

Many genes each add a small effect → many combinations → a smooth range of phenotypes.

Key words: range

154.22Pearson Edexcel focus

What shape of graph does a polygenic characteristic usually give?

Reveal answer

A bell-shaped (normal distribution) curve, plotted as a histogram.

Key words: bell

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