What is meant by the term polygenic?
Reveal answer
Influenced by alleles at several gene loci.
Key words: polygenic
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Influenced by alleles at several gene loci.
Key words: polygenic
Variation across a measurable range with many intermediate values.
Key words: continuous variation
Mainly controlled by one gene locus in the model.
Key words: monogenic
Pattern of values and their frequencies in a dataset.
Key words: distribution
Monogenic model: One. Polygenic model: Many.
Key words: Number of main loci
Monogenic model: Often discrete. Polygenic model: Often continuous.
Key words: Phenotype categories
Monogenic model: Simple ratios may apply. Polygenic model: Many combinations blur ratios.
Key words: Expected ratios
Monogenic model: Can occur. Polygenic model: Often substantial.
Key words: Environmental influence
Monogenic model: ABO group. Polygenic model: Height.
Key words: Example
False. Many loci contribute, so simple dominance at one locus cannot describe the whole trait.
False. It can arise from many genes plus environmental effects.
False. They influence potential, while environment and development modify outcome.
Skin colour (also height and eye colour).
Key words: skin colour
Many genes each add a small effect → many combinations → a smooth range of phenotypes.
Key words: range
A bell-shaped (normal distribution) curve, plotted as a histogram.
Key words: bell