How does blood clot?
Reveal answer
Platelets release chemicals → fibrinogen → fibrin mesh → traps red cells.
Key words: fibrin
3(h) TRANSPORT · RECALL
3.14B Platelets and blood clotting
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Which soluble plasma protein becomes fibrin?
Reveal answer
Fibrinogen.
Key words: fibrinogen
Why does clotting matter?
Reveal answer
Stops blood loss and blocks entry of pathogens.
Key words: pathogens
Which inherited condition slows clotting?
Reveal answer
Haemophilia.
Key words: haemophilia
What is meant by the term clotting?
Reveal answer
Series of reactions forming a solid seal after vessel damage.
Key words: clotting
What is meant by the term fibrin?
Reveal answer
Insoluble protein fibres forming a clot mesh.
Key words: fibrin
What is meant by the term fibrinogen?
Reveal answer
Soluble plasma protein converted to fibrin.
Key words: fibrinogen
What is meant by the term thrombus?
Reveal answer
Blood clot formed within a vessel.
Key words: thrombus
Helpful and harmful clotting: for Cut vessel, give the process and the consequence.
Reveal answer
Process: Platelet plug and fibrin mesh. Consequence: Limits blood loss.
Key words: Cut vessel
Helpful and harmful clotting: for Broken skin, give the process and the consequence.
Reveal answer
Process: Stable barrier forms. Consequence: Reduces pathogen entry.
Key words: Broken skin
Helpful and harmful clotting: for Internal thrombus, give the process and the consequence.
Reveal answer
Process: Clot forms in vessel. Consequence: Can reduce/stop blood flow.
Key words: Internal thrombus
Helpful and harmful clotting: for Healing tissue, give the process and the consequence.
Reveal answer
Process: Clot later removed/remodelled. Consequence: Normal circulation restored.
Key words: Healing tissue
True or false, and why? “Platelets alone become the entire clot.”
Reveal answer
False. They form a plug and initiate fibrin formation; fibrin stabilises it.
True or false, and why? “A scab is made only of dried blood cells.”
Reveal answer
False. It derives from a clot containing fibrin, platelets and trapped cells.
True or false, and why? “All clotting is beneficial.”
Reveal answer
False. Internal thrombosis can block blood flow.