PAPER 2 · QUESTION 1 STYLE · MODULAR UNIT 2

A tube the width of a drinking straw

330 words over 29 numbered lines, then 7 parts worth 13 marks (Modular Unit 2 (4WBI2) style, 12–13 marks). Read the article, answer each part, then open its mark scheme and set your mark.

4WBI213 marksabout 16 minutes

Article

Illustrative article written for Scholar Lab, not a Pearson text. The biology is real; the studies, people and figures are invented or rounded for practice.

A tube the width of a drinking straw

The heart is made of muscle that never rests. Like every other tissue,

heart muscle needs a constant supply of oxygen and glucose. These are

delivered by the coronary arteries, which branch over the outside of

the heart. Each one is only about as wide as a drinking straw. The

heart beats about seventy times a minute at rest, pumping blood from

the right ventricle to the lungs and from the left ventricle to the

rest of the body.

In coronary heart disease, fatty material builds up in the walls of

the coronary arteries. The lumen becomes narrower, and less blood can

flow through. A patient may feel chest pain during exercise, when the

heart beats faster and needs more oxygen. If a blood clot forms on the

fatty material, the artery can be blocked completely. The heart muscle

beyond the blockage starts to die within minutes. This is a heart

attack.

Arteries carry blood away from the heart at high pressure. They have

thick walls containing muscle and elastic tissue, which stretch and

recoil as each surge of blood passes. Damage to the inner lining of an

artery makes it easier for fatty material to build up.

Some risk factors for coronary heart disease cannot be changed, such

as age and a family history of the disease. Others can, including

smoking, high blood pressure, a diet high in saturated fat and a lack

of exercise. Figure 1 shows illustrative data from a study that

followed a large group of middle-aged adults for ten years.

A narrowed coronary artery can be widened by a stent. A doctor passes

a thin tube into an artery in the wrist or groin and guides it to the

heart. A tiny balloon is inflated inside the narrow section, and a

mesh tube is left in place to hold the artery open. Most patients go

home the next day. They are then advised to stop smoking, to eat less

saturated fat and to exercise regularly.

Figure 1 Heart attacks in adults with different risk factors

Bar chart of heart attacks per 1,000 people per year. No smoking and normal blood pressure: 2. Smoker: 5. High blood pressure: 4. Smoker with high blood pressure: 10.NeitherSmokerHigh bloodpressureSmoker and highblood pressure024681012Risk factorsHeart attacks per 1,000 people per year
Illustrative data: mean number of heart attacks per 1,000 people per year over a ten-year study.

Read the article and study the figure. Use the information in the article and your own knowledge to answer the questions. The lines in brackets show where to look; select them to highlight the text.

Use the information in the article and your own knowledge to answer the questions. The lines in brackets show you where to look; select them to highlight the text.

(a)

State what is meant by the term risk factor.

(1)
(b)

Name the blood vessels that supply the heart muscle with oxygen and glucose.

(1)
(c)

Describe what Figure 1 shows about the effect of having more than one risk factor.

(2)
(d)

Use Figure 1 to calculate how many times more heart attacks there were in smokers with high blood pressure than in people with neither risk factor.

(2)
(e)

Explain how the structure of an artery suits it to carrying blood at high pressure.

(2)
(f)

Explain why heart rate increases during exercise.

(3)
(g)

Suggest why patients who have had a stent fitted are still advised to stop smoking and eat less saturated fat.

(2)

Total for this question: 13 marks

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